NBUVB [311-312 nm] is now the gold standard for the treatment of skin disorders. At this wavelength, there is a decrease in the erythemogenic wavelength with a 5-fold increase in longer wavelengths resulting in an increased therapeutic effect. NBUVB is beneficial in the treatment of vitiligo, psoriasis, atopic dermatitis, chronic pruritus, and other inflammatory skin diseases. It is a safe and effective treatment.
The advantages of NBUVB are:
1) no need for eye protection during the post-treatment period,
2) safe in children and pregnant women, and
3) easy to administer.
The combination of various drugs with NBUVB is used to achieve a faster and higher clearance rate and a longer disease-free interval with a decrease in the cumulative dose. These include systemic agents such as methotrexate, cyclosporine, systemic retinoids, antioxidants, and topicals such as tacrolimus, pimecrolimus, vitamin D analogues, retinoids, glucocorticoids, emollients, and saltwater baths.